C12orf29 (N-term) Rabbit Polyclonal Antibody
Other products for "C12orf29"
Specifications
Product Data | |
Applications | FC, IF, IHC, WB |
Recommended Dilution | ELISA: 1/1000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Immunofluorescence: 1/10-1/50. Flow Cytometry: 1/10-1/50. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of Human CL029 |
Specificity | This antibody recognizes CL029 (N-term) |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide |
Concentration | lot specific |
Purification | Peptide Affinity Chromatography on Protein A |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 37490 Da |
Gene Name | Homo sapiens chromosome 12 open reading frame 29 (C12orf29) |
Database Link | |
Background | Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf29 gene product has been provisionally designated C12orf29 pending further characterization. |
Synonyms | DKFZp313K0436; DKFZp434N2030; DKFZp686L04169; FLJ38158; MGC102978 |
Reference Data |
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