CNDP1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP50983PU-N

CNDP1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CNDP1 Antibody (C-term) in CEM cell line lysates (35ug/lane). CNDP1 (arrow) was detected using the purified Pab.

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  Formalin-fixed and paraffin-embedded human brain tissue reacted with CNDP1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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  CNDP1 Antibody (C-term) flow cytometry analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/50 - 1/100.
  Flow cytometry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 422~451 amino acids from the C-terminal region of human CNDP1
• Specificity: This antibody reacts to CNDP1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 56692 Da
• Gene Name: carnosine dipeptidase 1
• Database Link:
  Entrez Gene 84735 Human
  UniProt ID Q96KN2
• Background: CNDP1 encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This protein contains trinucleotide (CTG) repeat length polymorphism in the coding region.
• Synonyms: Beta-Ala-His dipeptidase, Carnosine dipeptidase 1, CNDP dipeptidase 1, Serum carnosinase, CN1, CPGL2

Reference Data

• Protein Families: Protease, Secreted Protein
• Protein Pathways: beta-Alanine metabolism, Histidine metabolism, Metabolic pathways