Cathepsin O (CTSO) (N-term) Rabbit Polyclonal Antibody

CAT#: AP51133PU-N

Cathepsin O (CTSO) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

CTSO Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CTSO antibody detected the CTSO protein (arrow).

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  CTSO Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CTSO Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 76-106 amino acids from the N-terminal region of human CTSO
• Specificity: This antibody reacts to CTSO.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 35958 Da
• Gene Name: Homo sapiens cathepsin O (CTSO)
• Database Link:
  Entrez Gene 1519 Human
• Background: The protein encoded by the gene is a cysteine proteinase and a member of the papain superfamily. This proteolytic enzyme is involved in cellular protein degradation and turnover. The recombinant form of this enzyme was shown to degrade synthetic peptides typically used as substrates for cysteine proteinases and its proteolytic activity was abolished by an inhibitor of cyteine proteinase.
• Synonyms: CTSO, CTSO1

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome