DEGS2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51233PU-N

DEGS2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of DEGS2 Antibody (C-term) in Hela cell line lysates (35ug/lane). This demonstrates the DEGS2 antibody detected the DEGS2 protein (arrow).

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  Formalin fixed and paraffin embedded human kidney tissue reacted with DEGS2 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 268-298 amino acids from the C-terminal region of human DEGS2
• Specificity: This antibody recognizes Human DEGS2 (C-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: delta(4)-desaturase, sphingolipid 2
• Database Link:
  Entrez Gene 123099 Human
  UniProt ID Q6QHC5
• Background: DEGS2 encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase.
• Synonyms: Degenerative spermatocyte homolog 2, C14orf66, DES2
• Note: Molecular Weight: 37197 Da

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism