EDEM3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51363PU-N

EDEM3 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of EDEM3 Antibody (C-term) in A2058 cell line lysates (35ug/lane). This demonstrates the EDEM3 antibody detected the EDEM3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 773-802 amino acids from the C-terminal region of human EDEM3
• Specificity: This antibody recognizes Human EDEM3 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens ER degradation enhancer, mannosidase alpha-like 3 (EDEM3), transcript variant 2
• Database Link:
  Entrez Gene 80267 Human
• Background:
  Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).
• Synonyms: C1orf22
• Note: Molecular Weight: 104664 Da