FBLIM1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51614PU-N

FBLIM1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of FBLIM1 Antibody (C-term) in A549 cell line lysates (35ug/lane). This demonstrates the FBLIM1 antibody detected the FBLIM1 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue reacted with FBLIM1 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 301-331 amino acids from the C-terminal region of Human FBLIM1
• Specificity: This antibody recognizes Human FBLIM1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens filamin binding LIM protein 1 (FBLIM1), transcript variant 2
• Database Link:
  Entrez Gene 54751 Human
• Background: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Synonyms: FBLP-1, FBLP1, Migfilin, MIG2-interacting protein
• Note: Molecular Weight: 40670 Da