FPR3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51721PU-N

FPR3 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of FPR3 Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the FPR3 antibody detected the FPR3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 321-351 amino acids from the C-terminal region of Human FMLP-related receptor II
• Specificity: This antibody recognizes Human FMLP-related receptor II / FPR3 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens formyl peptide receptor 3 (FPR3)
• Database Link:
  Entrez Gene 2359 Human
• Background: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
• Synonyms: N-formyl peptide receptor 3, Formyl peptide receptor-like 2, FPR3, FPRH1, FPRL2, FMLP-R-II
• Note: Molecular Weight: 39965 Da

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction