FRAT2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51723PU-N

FRAT2 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of FRAT2 Antibody (C-term) in ZR-75-1, K562 cell line lysates (35ug/lane). This demonstrates the FRAT2 antibody detected the FRAT2 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma reacted with FRAT2 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

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  Confocal immunofluorescent analysis of FRAT2 Antibody (C-term) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunofluorescence: 1/10-1/50.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 210-233 amino acids from the C-terminal region of human FRAT2
• Specificity: This antibody recognizes Human FRAT2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens frequently rearranged in advanced T-cell lymphomas 2 (FRAT2)
• Database Link:
  Entrez Gene 23401 Human
• Background: The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.
• Synonyms: GSK-3-binding protein Frat-2
• Note: Molecular Weight: 24051 Da

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: Wnt signaling pathway