GBE1 (Center) Rabbit Polyclonal Antibody

CAT#: AP51790PU-N

GBE1 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of GBE1 Antibody (Center) in HL-60 cell line lysates (35ug/lane).

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  Western blot analysis of GBE1 Antibody (Center) in mouse liver tissue lysates (35ug/lane).

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  Confocal immunofluorescent analysis of GBE1 Antibody (Center) with HepG2 cell followed by Alexa Fluor? 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunofluorescence: 1/10-1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 534~564 amino acids from the Central region of human GBE1
• Specificity: This antibody recognizes Human and Mouse GBE1 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens glucan (1,4-alpha-), branching enzyme 1 (GBE1)
• Database Link:
  Entrez Gene 2632 Human
• Background: GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease.
• Synonyms: Glycogen-branching enzyme, Brancher enzyme
• Note: Molecular Weight: 80460 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Starch and sucrose metabolism