KAT2A (C-term) Rabbit Polyclonal Antibody

CAT#: AP52039PU-N

KAT2A (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of KAT2A / GCN5L2 Antibody (C-term) in mouse Neuro-2a cell line lysates (35ug/lane).

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  Flow cytometric analysis of Neuro-2a cells using KAT2A / GCN5L2 Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 806-837 amino acids from the C-terminal region of Human KAT2A / GCN5L2
• Specificity: This antibody recognizes Human and Mouse KAT2A / GCN5L2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens K(lysine) acetyltransferase 2A (KAT2A)
• Database Link:
  Entrez Gene 14534 MouseEntrez Gene 2648 Human
• Background:
  KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).
• Synonyms: Histone acetyltransferase KAT2A, Histone acetyltransferase GCN5, HsGCN5, HGCN5, Lysine acetyltransferase 2A, STAF97
• Note: Molecular Weight: 93926 Da

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Notch signaling pathway