MFGE8 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52057PU-N

MFGE8 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Lactadherin Antibody (C-term) in Hela cell line lysates (35ug/lane).

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  Flow cytometric analysis of Hela cells using Lactadherin Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: Western Blot: 1/1000.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 315-345 amino acids from the C-terminal region of Human Lactadherin
• Specificity: This antibody recognizes Human Lactadherin (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens milk fat globule-EGF factor 8 protein (MFGE8), transcript variant 2
• Database Link:
  Entrez Gene 4240 Human
• Background: HMFG plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. Medin is the main constituent of aortic medial amyloid.
• Synonyms: MFGE8, Milk fat globule-EGF factor 8, HMFG, Breast epithelial antigen BA46, MFGM
• Note: Molecular Weight: 43123 Da