HMG4 (HMGB3) (Center) Rabbit Polyclonal Antibody

CAT#: AP52060PU-N

HMG4 (HMGB3) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of HMGB3 Antibody (Center) in NCI-H292 cell line lysates (35ug/lane). This demonstrates the HMGB3 antibody detected the HMGB3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 49-79 amino acids from the Central region of human HMGB3
• Specificity: This antibody recognizes Human HMGB3 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens high mobility group box 3 (HMGB3), transcript variant 2
• Database Link:
  Entrez Gene 3149 Human
• Background:
  HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).
• Synonyms: HMGB-3, HMG2A, HMG4, High mobility group protein B3, High mobility group protein 4, HMG-4, High mobility group protein 2a, HMG-2a
• Note: Molecular Weight: 22980 Da

Reference Data

• Protein Families: Transcription Factors