HNF1 beta (HNF1B) (C-term) Rabbit Polyclonal Antibody

CAT#: AP52066PU-N

HNF1 beta (HNF1B) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of HNF1 beta / TCF2 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the HNF1B antibody detected the HNF1B protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 505-536 amino acids from the C-terminal region of human HNF1B
• Specificity: This antibody recognizes Human HNF1 beta / TCF2 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens HNF1 homeobox B (HNF1B), transcript variant 1
• Database Link:
  Entrez Gene 6928 Human
• Background: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene
• Synonyms: HNF-1-beta, HNF-1B, Transcription factor 2, TCF-2, vHNF1, LFB3
• Note: Molecular Weight: 61324 Da

Reference Data

• Protein Families: Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors
• Protein Pathways: Maturity onset diabetes of the young