IL2 Receptor gamma (IL2RG) (N-term) Rabbit Polyclonal Antibody

CAT#: AP52197PU-N

IL2 Receptor gamma (IL2RG) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CD132 / IL2RG Antibody (N-term) in HL-60 cell line lysates (35ug/lane). IL2RG (arrow) was detected using the purified Pab.

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  Flow cytometric analysis of HL-60 cells using CD132 / IL2RG Antibody (N-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution:

  Western Blot: 1/1000.
  Flow Cytometry: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 76 - 101 amino acids from the N-terminal region of Human CD132 / IL2RG
• Specificity: This antibody recognizes Human CD132 / IL2RG (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens interleukin 2 receptor subunit gamma (IL2RG)
• Database Link:
  Entrez Gene 3561 Human
• Background:
  IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
• Synonyms: Gamma-C, p64, Interleukin-2 receptor gamma chain
• Note: Molecular Weight: 42287 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway, Primary immunodeficiency