KCND1 (N-term) Rabbit Polyclonal Antibody
Other products for "KCND1"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 117-147 amino acids from the N-terminal region of human KCND1 |
Specificity | This antibody recognizes Human KCND1 (N-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens potassium voltage-gated channel subfamily D member 1 (KCND1) |
Database Link | |
Background | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This gene is expressed at moderate levels in all tissues analyzed, with lower levels in skeletal muscle. |
Synonyms | Voltage-gated potassium channel subunit Kv4.1 |
Note | Molecular Weight: 71330 Da |
Reference Data | |
Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
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