L1CAM (C-term) Rabbit Polyclonal Antibody
Other products for "L1CAM"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | This antibody is suitable for Western blotting. The suggested dilution is: 1/100-1/500. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 1153-1182aa) of human CD171 / L1CAM. |
Specificity | This antibody detects CD171 / L1CAM at C-term. |
Formulation | PBS with 0.09% (W/V) Sodium Azide. State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch.
|
Gene Name | Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1 |
Database Link | |
Background | L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. |
Synonyms | N-CAM L1, CAML1, MIC5 |
Note | Molecular Weight: 140003 Da |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Axon guidance, Cell adhesion molecules (CAMs) |
Documents
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.