THRAP5 (MED16) (Center) Rabbit Polyclonal Antibody

CAT#: AP52650PU-N

THRAP5 (MED16) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of MED16 Antibody (Center) in 293 cell line lysates (35ug/lane). This demonstrates the MED16 antibody detected the MED16 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of human MED16
• Specificity: This antibody recognizes Human MED16 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens mediator complex subunit 16 (MED16)
• Database Link:
  Entrez Gene 10025 Human
• Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
• Synonyms: DRIP92, THRAP5, Mediator complex subunit 16
• Note: Molecular Weight: 72kd Isoform 5. 96793 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors