nkx6.1 (NKX6-1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP52893PU-N

nkx6.1 (NKX6-1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in mouse liver tissue lysates (35ug/lane) using NKX6-1 antibody. (C-term). This demonstrates this antibody detected the NKX6-1 protein (arrow).

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  Western blot analysis in A549 cell line lysates (35ug/lane) using NKX6-1 antibody. (C-term). This demonstrates this antibody detected the NKX6-1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/100-1/500.
  Enzyme immunoassay: 1/1000.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 284-314aa) of human NKX6-1
• Specificity: This antibody recognizes NKX6-1 at C-term.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: NK6 homeobox 1
• Database Link:
  Entrez Gene 18096 MouseEntrez Gene 4825 Human
  UniProt ID P78426
• Background: In the pancreas, NKX6-1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes. [Iype et al., 2004; PubMed 15056733]
• Synonyms: NKX6A
• Note: Molecular Weight: 37849 Da

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Maturity onset diabetes of the young