Progesterone Receptor (PGR) (Center) Rabbit Polyclonal Antibody
CAT#: AP53273PU-N
Progesterone Receptor (PGR) (Center) rabbit polyclonal antibody, Aff - Purified
Other products for "PGR"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. Immunohistochemistry on Paraffin Sections: 1/10-1/50. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 348-377 amino acids from the Central region of human Progesterone receptor |
Specificity | This antibody recognizes Human Progesterone receptor (Center). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens progesterone receptor (PGR), transcript variant 2 |
Database Link | |
Background | This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined. |
Synonyms | PR, PGR, NR3C3 |
Note | Molecular Weight: 98981 Da |
Reference Data | |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Protein Pathways | Oocyte meiosis, Progesterone-mediated oocyte maturation |
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