PIGP (N-term) Rabbit Polyclonal Antibody

CAT#: AP53299PU-N

PIGP (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in T47D cell line lysates (35ug/lane) using PIGP antibody. (N-term). This demonstrates the PIGP antibody detected the PIGP protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/1000.
  
  

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 2-30 aa) of human PIGP.
• Specificity: This antibody recognizes PIGP at N-term.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens phosphatidylinositol glycan anchor biosynthesis class P (PIGP), transcript variant 1
• Database Link:
  Entrez Gene 51227 Human
• Background: The PIGP gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
• Synonyms: DSCR5, DCRC, DSCRC, DCRC-S, Down syndrome critical region protein 5
• Note: Molecular Weight: 18059 Da

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways