Phospholipase C beta 1 (PLCB1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP53333PU-N

Phospholipase C beta 1 (PLCB1) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of PLCB1 Antibody (C-term) in HL-60 cell line lysates (35ug/lane). PLCB1 (arrow) was detected using the purified Pab.

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  Flow cytometric analysis of HL-60 cells using PLCB1 Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1155~1184 amino acids from the C-terminal region of human PLCB1
• Specificity: This antibody recognizes Human PLCB1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 1
• Database Link:
  Entrez Gene 23236 Human
• Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
• Synonyms: Phospholipase C-I, PLC beta1, PLC-I, Phospholipase C-beta-1, PLC-beta-1, KIAA0581
• Note: Molecular Weight: 138567 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway, Chemokine signaling pathway, Gap junction, GnRH signaling pathway, Huntington's disease, Inositol phosphate metabolism, Long-term depression, Long-term potentiation, Melanogenesis, Metabolic pathways, Phosphatidylinositol signaling system, Vascular smooth muscle contraction, Wnt signaling pathway