PLC delta 3 (PLCD3) (N-term) Rabbit Polyclonal Antibody
Other products for "PLCD3"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 59-89 amino acids from the N-terminal region of human PLCD3 |
Specificity | This antibody recognizes Human and Mouse PLCD3 (N-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens phospholipase C delta 3 (PLCD3) |
Database Link | |
Background | This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq]. |
Synonyms | Phospholipase C-delta-3, Phospholipase C delta 3, PLC-delta-3 |
Note | Molecular Weight: 89258 Da |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Calcium signaling pathway, Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system |
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