POLR1B (N-term) Rabbit Polyclonal Antibody
Other products for "POLR1B"
Specifications
Product Data | |
Applications | FC, IHC, WB |
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. Flow Cytometry: 1/10-1/50. Immunohistochemistry on Paraffin Sections: 1/10-1/50. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | conjugated synthetic peptide between 88-117 amino acids from the N-terminal region of human POLR1B |
Specificity | This antibody recognizes Human POLR1B (N-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinitty Chromatography on Protein A |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens polymerase (RNA) I polypeptide B, 128kDa (POLR1B), transcript variant 2 |
Database Link | |
Background | Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]). |
Synonyms | RNA polymerase I subunit 2, RPA135 |
Note | Molecular Weight: 128229 Da |
Reference Data | |
Protein Families | Transcription Factors |
Protein Pathways | Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase |
Documents
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