RNF34 (C-term) Rabbit Polyclonal Antibody

CAT#: AP53691PU-N

RNF34 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

RNF34 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the RNF34 antibody detected the RNF34 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 282-311 amino acids from the C-terminal region of human RNF34
• Specificity: This antibody reacts to RNF34.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 41641 Da
• Gene Name: Homo sapiens ring finger protein 34 (RNF34), transcript variant 2
• Database Link:
  Entrez Gene 80196 Human
• Background: The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
• Synonyms: CARP1, CARP-1, RIFF

Reference Data

• Protein Families: Druggable Genome