SCARA5 (C-term) Rabbit Polyclonal Antibody

CAT#: AP53807PU-N

SCARA5 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of SCARA5 Antibody (C-term) in mouse heart tissue lysates (15 ug/lane). This demonstrates the SCARA5 antibody detected SCAR5 protein (arrow).

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  Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human stomach tissue stained with SCARA5 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SCAR5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 392-421 amino acids from the C-terminal region of Human SCAR5 (NP_776194.2)
• Specificity: Recognizes SCARA5 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens scavenger receptor class A member 5 (SCARA5)
• Database Link:
  Entrez Gene 71145 MouseEntrez Gene 286133 Human
• Background: SCARA5 (scavenger receptor class A member 5), also known as Tesr, is a 495 amino acid cell membrane protein. SCARA5 is expressed at high levels in testis, with highest levels specifically found in specific populations of epithelial cells and Sertoli cells. SCARA5 forms a homotrimer single-pass type II membrane complex present on the surface of the plasma membrane. Cells transfected with SCARA5 were able to bind particular gram-positive and gram-negative bacteria, suggesting a possible role for SCARA5 in immunity to infection. It has also been suggested that SCARA5 may be involved in transferrin delivery pathways. Expressed as four isoforms produced by alternative splicing, SCARA5 contains one collagen-like domain and one SRCR domain.
• Synonyms: FLJ23907; MGC45780; NET33; Tesr
• Note: Molecular Weight: 53994 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane