SGSH (C-term) Rabbit Polyclonal Antibody

CAT#: AP53892PU-N

SGSH (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of SGSH Antibody (C-Term) in HepG2 cell line lysates (35ug/lane). SGSH (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 427~457 amino acids from the C-terminal region of Human SGSH.
• Specificity: Recognizes Sulphamidase / SGSH (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens N-sulfoglucosamine sulfohydrolase (SGSH)
• Database Link:
  Entrez Gene 6448 Human
• Background: SGSH is one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.
• Synonyms: Sulfoglucosamine sulfamidase, HSS
• Note: Molecular Weight: 56695 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycosaminoglycan degradation, Lysosome, Metabolic pathways