SHANK2 (Center) Rabbit Polyclonal Antibody
Other products for "SHANK2"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 879-908 amino acids from the Central region of Human SHANK2. |
Specificity | This antibody recognizes Mouse SHANK2 (Center). Other species not tested. |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 158822 Da |
Gene Name | Homo sapiens SH3 and multiple ankyrin repeat domains 2 (SHANK2), transcript variant 1 |
Database Link | |
Background | This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq]. |
Synonyms | Cortactin-binding protein 1, CORTBP1, PROSAP1, SPANK-3, SPANK3, KIAA1022 |
Reference Data |
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