THEMIS (C-term) Rabbit Polyclonal Antibody

CAT#: AP54239PU-N

THEMIS (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

THEMIS Antibody (C-term) western blot analysis in mouse liver tissue lysates (35 ug/lane). This demonstrates the THEMIS antibody detected the THEMIS protein (arrow).

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  THEMIS Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human thymoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of THEMIS Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
  Immunohistochemistry on paraffin sections: 1:50~100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 566-595 amino acids from the C-terminal region of human THEMIS
• Specificity: This antibody detects THEMIS (C-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens thymocyte selection associated (THEMIS), transcript variant 2
• Database Link:
  Entrez Gene 210757 MouseEntrez Gene 387357 Human
• Background: This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants.
• Synonyms: Protein Themis, Grb2-associating protein, Gasp, Protein thylex
• Note: Molecular Weight: 59kd Isoform4; 73452 Da