Uroplakin Ib (UPK1B) (Center) Rabbit Polyclonal Antibody
CAT#: AP54476PU-N
Uroplakin Ib (UPK1B) (Center) rabbit polyclonal antibody, Aff - Purified
Other products for "UPK1B"
Specifications
Product Data | |
Applications | FC, IHC, WB |
Recommended Dilution | Western blot: 1:1,000. Immunohistochemistry on paraffin sections: 1:50~100. Flow cytometry: 1:10~50. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 159~188 amino acids from the Central region of human UPK1B |
Specificity | This antibody detects Uroplakin-1b (UPK1B) (Center). |
Formulation | PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A column followed by peptide affinity purification |
Storage | Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens uroplakin 1B (UPK1B) |
Database Link | |
Background | UPK1B is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. |
Synonyms | UP1b, Uroplakin Ib, UPIb, Tetraspanin-20, TSPAN20, Tspan-20 |
Note | Molecular Weight: 29643 Da |
Reference Data | |
Protein Families | Transmembrane |
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