UROC1 (Center) Rabbit Polyclonal Antibody

CAT#: AP54483PU-N

UROC1 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

UROC1 Antibody (Center) western blot analysis in K562 cell line lysates (35 ug/lane). This demonstrates the UROC1 antibody detected the UROC1 protein (arrow).

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  UROC1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of UROC1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
  Immunohistochemistry on paraffin sections: 1:10~50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 409-437 amino acids from the Central region of human UROC1
• Specificity: This antibody detects UROC1 (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens urocanate hydratase 1 (UROC1), transcript variant 2
• Database Link:
  Entrez Gene 131669 Human
• Background: This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: Urocanate hydratase
• Note: Molecular Weight: 74831 Da

Reference Data

• Protein Pathways: Histidine metabolism, Metabolic pathways