CD57 / HNK1 Mouse Monoclonal Antibody [Clone ID: VC1.1]

CAT#: BM2344

CD57 / HNK1 mouse monoclonal antibody, clone VC1.1, Purified

Specifications

Product Data

• Clone Name: VC1.1
• Applications: FC, IHC, WB
• Recommended Dilution: Suitable for use in Flow Cytometry (1 µg/1x10e6 cells/test), Western blotting and Immunohistology on formalin fixed paraffin embedded tissue sections.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Cat unfixed cortical homogenate area 17
• Specificity: Recognizes a (Mr 110 kDa) carbohydrate molecule on Myeloid cells, known as CD57. This antibody blocks binding of HNK-1 (Leu. 7) antibody.(3)
• Formulation: 0.01 M PBS, pH 7.2 containing 1% BSA as stabilizer and 0.09% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein A chromatography.
• Storage: Store the antibody undiluted at 2-8°C for up to one month or in aliquots at -20°C long term. Avoid repeted freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: The CD57 surface antigen is associated with myelin-associated glycoprotein (MAG).(1). The antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-Lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.
• Synonyms: HNK-1, LEU7, NK-1, NK-Cell marker, NK1