Integrin alpha 4 (ITGA4) Mouse Monoclonal Antibody [Clone ID: BU49]

CAT#: BM2458F

Integrin alpha 4 (ITGA4) mouse monoclonal antibody, clone BU49, FITC

Specifications

Product Data

• Clone Name: BU49
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of Neat-1/10 diluted antibody to label 1x10e6 cells in 100 µl.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Hyatt myeloma cell line.
• Specificity: This antibody recognizes CD49d, also known as integrin alpha 4.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as presrevative and 1% BSA as stabilizer
  Label: FITC
  State: Liquid purified IgG fraction
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: FITC
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  This product is photosensitive and should be protected from light.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 3676 Human
• Background: CD49d is a 150kD transmembrane glycoprotein, which may be cleaved to form 70kD and 80kD fragments. CD49d is expressed on a broad range of cells including lymphocytes, monocytes, eosinophils and thymocytes. The CD49d molecule forms heterodimers with either integrin Beta 1 (to form VLA-4) or beta 7 (to form alpha4 beta7), which mediate cell adhesion to VCAM-1and fibronectin.
• Synonyms: Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4