Factor XI (F11) Mouse Monoclonal Antibody [Clone ID: hfXI-2]

CAT#: BM2634

Factor XI (F11) mouse monoclonal antibody, clone hfXI-2, Azide Free

Specifications

Product Data

• Clone Name: hfXI-2
• Applications: ELISA, FN, R, WB
• Recommended Dilution: Inhibitory in clotting assays.
  Useful for purification of Factor XI.
  Western blot (non-reduced samples only, band size 160 kD).
  RIA.
  ELISA.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Human Factor XI
• Specificity: Reacts with human Factor XI.
• Formulation: 50% (vol/vol) glycerol/water) without preservatives
  State: Azide Free
  State: Liquid purified Ig fraction (>95% pure).
• Concentration: lot specific
• Purification: Ammonium sulfate precipitation, ion exchange chromatography and gel filtration
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 2160 Human
• Background: Factor X is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a haemorrhagic condition of variable severity.
• Synonyms: Plasma thromboplastin antecedent, PTA, FX1