IL1 Receptor II (IL1R2) Mouse Monoclonal Antibody [Clone ID: 49/20]

CAT#: BM985

IL1 Receptor II (IL1R2) mouse monoclonal antibody, clone 49/20, Purified

Specifications

Product Data

• Clone Name: 49/20
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: R-DNA. Human interleukin-1 soluble receptor, type 1 expressed in insect cell line Sf.
• Specificity: This antibody reacts to Interleukin 1 Receptor Type I. Does not react with rmIL-1 RI or rhIL-1 RII in either Western blotting or ELISA.
• Formulation: PBS buffer, pH 7.2 with 5% trehalose
  State: Purified
  State: Liquid purified IgG
• Concentration: 0.5 mg/ml
• Purification: Chromatography on Protein G
• Gene Name: interleukin 1 receptor type 2
• Database Link:
  Entrez Gene 7850 Human
• Background: IL1 Receptor II is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
• Synonyms: Interleukin-1 receptor type II, IL-1R-2, IL-1R-beta, CDw121b, IL1RB