Apolipoprotein CIII (APOC3) Goat Polyclonal Antibody

CAT#: BP2083B

Apolipoprotein CIII (APOC3) goat polyclonal antibody, Biotin

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: Can be used to detect the existence of Apo CIII in plasma and lipoproteins, for immunoassay and immunoblotting.
  Dilution for immunoblot and ELISA range: 2,000 to 20,000.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Purified human Apolipoprotein CIII
• Specificity: Binds to Apo CIII.
  No cross-reaction to Apo AI, Apo AII, Apo B-100, Apo CI, Apo CII and Apo E.
• Formulation: 10 mM PBS, 0.15 M NaCl, pH 7.2 with 0.02% sodium azide as preservative.
  Label: Biotin
  State: Liquid purified Ig fraction.
• Reconstitution Method: Reconstitutein 0.5ml distilled water.
• Concentration: lot specific
• Purification: Human Apo CIII-Sepharose affinity column.
• Conjugation: Biotin
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 345 Human
• Background: At least 9 distinct polymorphic forms of apolipoproteins are known. The apolipoproteins act as stabilizers of the intact lipoprotein particles. Quantitative measurements of HDL, LDL and VLDL particles in human serum are often used to estimate an individuals' relative risk of coronary heart disease. In addition, quantitative immunological measurements of certain apolipoproteins (especially A1 and B) have been suggested to be more accurate estimators of coronary heart disease than measurements of lipoprotein particles (especially HDL and LDL).
  Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. It inhibits lipoprotein lipase and hepatic lipase and it is thought to delay catabolism of triglyceride-rich particles. An increase in apoC-III levels induces the development of hypertriglyceridemia.
• Synonyms: Apolipoprotein C-III, Apolipoprotein C3, Apo-CIII, ApoC-III