Apolipoprotein E (APOE) Rabbit Polyclonal Antibody

CAT#: BP2159

Apolipoprotein E (APOE) rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: ID, WB
• Recommended Dilution: Radial immunodiffusion assay : 1/200.
  Immuno double- diffusion Rocket IEP.
  Western blot.
• Reactivities: Hamster
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Hamster Apolipoprotein E purified from Hamster plasma very low - and low density lipoprotein
• Specificity: Radial immunodiffusion, immunoblotting.
  Species-specific: extremely low recognition of human Apo AI. No data available regarding rat reactivity.
• Formulation: 0.05% Sodium Azide, 100 U/ml penicillin, 10µg/ml streptomycin, 25 ng/ml amphotericin B
  State: Serum
  State: Liquid neat, heat inactiveated, 0.22 µm filtered
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.
• Synonyms: ApoE, Apo-E