Transferrin (TF) Sheep Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA |
Recommended Dilution | ELISA (1/5K - 1/20K). |
Reactivities | Human |
Host | Sheep |
Clonality | Polyclonal |
Immunogen | Pure human transferrin prepared from pooled normal human serum. |
Specificity | This antibody detects Transferrin. Shows minimal cross reactivity with related serum proteins. |
Formulation | PBS, pH 7.2 without additives. State: Ig Fraction State: Liquid purified Ig fraction. Preservative: 0.09% Sodium Azide. |
Concentration | lot specific |
Purification | Antisera to human transferrin were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography on Protein G. |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Transferrin is an approximately 80 kDa blood plasma glycoprotein synthesised by the liver, which contains two specific high affinity iron (Fe3+) binding sites and is responsible for the transport and supply of an exchangeable pool of iron, through binding to cell surface transferrin receptors. Transferrin is the primary blood iron transport protein and under normal conditions, approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis. |
Synonyms | Serotransferrin, Siderophilin |
Reference Data |
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