Nucleotide binding protein like (NUBPL) Mouse Monoclonal Antibody [Clone ID: OTI7D6]
CAT#: CF503746
Carrier-free (BSA/glycerol-free) NUBPL mouse monoclonal antibody, clone OTI7D6 (formerly 7D6)
Formulation: Standard
Other products for "NUBPL"
Specifications
Product Data | |
Clone Name | OTI7D6 |
Applications | FC, WB |
Recommended Dilution | WB 1:2000, FLOW 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-250 of human NUBPL(NP_079428) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 33.9 kDa |
Gene Name | Homo sapiens nucleotide binding protein like (NUBPL), transcript variant 1, mRNA. |
Database Link | |
Background | This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the inner mitochondrial membrane. The respiratory complex I consists of 45 subunits and 8 iron-sulfur (Fe/S) clusters. This protein is an Fe/S protein that plays a critical role in the assembly of respiratory complex I, likely by transferring Fe/S into the Fe/S-containing complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding distinct isoforms have been identified. |
Synonyms | C14orf127; huInd1; IND1 |
Reference Data |
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