DOCK8 Mouse Monoclonal Antibody [Clone ID: OTI8D9]
CAT#: CF801833
Carrier-free (BSA/glycerol-free) DOCK8 mouse monoclonal antibody, clone OTI8D9 (formerly 8D9)
Formulation: Standard
Other products for "DOCK8"
Specifications
Product Data | |
Clone Name | OTI8D9 |
Applications | FC, WB |
Recommended Dilution | WB 1:500 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 84-405 of human DOCK8 (NP_982272) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 238.3 kDa |
Gene Name | Homo sapiens dedicator of cytokinesis 8 (DOCK8), transcript variant 1, mRNA. |
Database Link | |
Background | This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] |
Synonyms | HEL-205; MRD2; ZIR8 |
Reference Data |
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