JAK2 Mouse Monoclonal Antibody [Clone ID: OTI7D12]
CAT#: CF806794
Carrier-free (BSA/glycerol-free) JAK2 mouse monoclonal antibody, clone OTI7D12 (formerly 7D12)
Formulation: Standard
Other products for "JAK2"
Specifications
Product Data | |
Clone Name | OTI7D12 |
Applications | IHC |
Recommended Dilution | IHC 1:150 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 297-596 of human JAK2(NP_004963) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | Homo sapiens Janus kinase 2 (JAK2), transcript variant 1, mRNA. |
Database Link | |
Background | This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008] |
Synonyms | JTK10; THCYT3 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Adipocytokine signaling pathway, Chemokine signaling pathway, Jak-STAT signaling pathway |
Documents
Product Manuals |
FAQs |
Resources
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