Inositol Hexakisphosphate Kinase 2 (IP6K2) Mouse Monoclonal Antibody [Clone ID: OTI1F12]

CAT#: CF808811

Carrier-free (BSA/glycerol-free) IP6K2 mouse monoclonal antibody,clone OTI1F12

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IP6K2 (RC209533, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IP6K2 (1:500). Positive lysates LY414064 (100ug) and LC414064 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI1F12
• Applications: WB
• Recommended Dilution: WB 1:500
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-250 of human IP6K2(NP_057375) produced in E.coli.
• Formulation: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Homo sapiens inositol hexakisphosphate kinase 2 (IP6K2), transcript variant 1, mRNA.
• Database Link:
  NP_057375
  Entrez Gene 59268 RatEntrez Gene 76500 MouseEntrez Gene 51447 Human
  UniProt ID Q9UHH9
• Background: This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
• Synonyms: IHPK2; PIUS

Reference Data

• Protein Families: Druggable Genome