BCMA (TNFRSF17) Mouse Monoclonal Antibody [Clone ID: OTI11B1]

CAT#: CF813846

Carrier-free (BSA/glycerol-free) TNFRSF17 mouse monoclonal antibody, clone OTI11B1

Product Images

Flow cytometric analysis of living 293T cells co-transfected with pCMV6-ENTRY BCMA (Cat# RC208851) and pCMV6-ENTRY APRIL (Cat# RC221008) cDNAs (Red) or transfected with empty vector (Cat# PS100001, Blue) using anti-BCMA antibody (Cat# TA813846) compared to a nonspecific negative control antibody (Green). (1:100)

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  Flow cytometric analysis of living RPMI-8226 cells, using anti-BCMA antibody (Cat# TA813846, Red), compared to an isotype control (green), and a PBS control (blue). (1:100)

Specifications

Product Data

• Clone Name: OTI11B1
• Applications: FC
• Recommended Dilution: FC 1:100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant full length protein of human TNFRSF17/BCMA (NP_001183) produced in HEK293 cell.
• Formulation: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20.1 kDa
• Gene Name: Homo sapiens TNF receptor superfamily member 17 (TNFRSF17), mRNA.
• Database Link:
  NP_001183
  Entrez Gene 608 Human
  UniProt ID Q02223
• Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
• Synonyms: BCM; BCMA; CD269; TNFRSF13A

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction