Cd8b1 Mouse Monoclonal Antibody [Clone ID: F9(1)]

CAT#: CL011S

Cd8b1 mouse monoclonal antibody, clone F9(1), Supernatant

Specifications

Product Data

• Clone Name: F9(1)
• Applications: CT
• Recommended Dilution: Flow Cytometry.
• Reactivities: Mouse
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Recipient: ((B6xB6-Ly-2a)F1xB6-Ly-2a)) offspring (Ly-2a homozygous). Donor: B6-Ly-2a3a,H-2k. Fusion Partner: Spleen from immunized recipient fused with myeloma P3/X63-Ag8.
• Specificity: This Monoclonal antibody reacts with a sub-population of T-lymphocytes expressing the Ly-3.1 phenotype, but does not react with lymphocytes from mouse strains expressing the Ly-3.2 phenotype.
• Formulation: State: Supernatant
  State: Lyophilized Supernatant
• Reconstitution Method: Restore with 1.0 ml of distilled water
• Gene Name: Mus musculus CD8 antigen, beta chain 1 (Cd8b1)
• Database Link:
  Entrez Gene 12526 Mouse
• Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
• Synonyms: CD8B, CD8B1
• Note: This reagent is not sold sterile, but can be sterilized by filtration if necessary. To minimize loss of volume during
  filtration, dilute to the final working concentration in the appropriate medium before filtration.