Cd207 Rat Monoclonal Antibody [Clone ID: 923B7]

CAT#: DDX0373P-100

Cd207 rat monoclonal antibody, clone 923B7


USD 440.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 923B7
Applications FC, IHC
Recommended Dilution DDX0373P-50 / DDX0373P-100 Purified: IHC, Flow cytometry.
DDX0373A488-50 / DDX0373A488-100 Alexa-fluor®488: IF surface Flow cytometry.
DDX0373A546-50 / DDX0373A546-100 Alexa-fluor®546: IF. 
DDX0373A647-50 / DDX0373A647-100 Alexa-fluor®647: Flow cytometry.
DDX0373B-50 / DDX0373B-100 Biotin: Flow cytometry. 

Usage recommendation:
*This monoclonal antibody may be used between 5-20 μg/ml.
*Optimal dilution should be determined by each laboratory for each application.
*Coupled antibody: to maintain RT before using.
Reactivities Human, Mouse, Rat
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen Human Langerin-transfected eukaryotic cells.
Specificity Human Langerin (extracellular epitope). 
Species cross-reactivity: Rat, Mouse.
Formulation Purified: 100 μg in 200μl / 50 μg in 100 μl Tris-NaCl pH 8.
Coupled: 100 μg in 200μl / 50 μg in 100 μl PBS 50% glycerol.
State: Purified
Concentration lot specific
Purification Hyper-D ion exchange chromatography
Conjugation Unconjugated
Storage -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Gene Name CD207 antigen
Background Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck’s granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 2002 J Immunol, 168 : 782-792) (Douillard P et al, 2005 J Invest Dermatol, 125: 983–994).
Synonyms CLEC4K, Dendritic Cell Marker
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.