GCSF Receptor (CSF3R) Mouse Monoclonal Antibody [Clone ID: S-1268]

CAT#: DM1053

GCSF Receptor (CSF3R) mouse monoclonal antibody, clone S-1268, Purified

Specifications

Product Data

• Clone Name: S-1268
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Immunoblotting: Recognizes denatured G-CSFR following SDS-PAGE and blotting of 200 ug of cell lysate or following immunoprecipitation with polyclonal antibody followed by immunoblotting.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant MBP-GCSFR fusion protein.
• Specificity: Reactive with G-CSFR and does not cross-react with MBP or BSA (Bovine Serum Albumin).
• Formulation: 0.01M PBS, pH 7.2 without preservatives.
  State: Purified
  State: Lyophilized purified IgG fraction.
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G.
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens colony stimulating factor 3 receptor (CSF3R), transcript variant 1
• Database Link:
  Entrez Gene 1441 Human
  UniProt ID Q99062
• Background: The protein encoded by the GCSF Receptor gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, of which three are membrane-bound and the one secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
• Synonyms: G-CSF-R, GCSFR, GCSF Receptor, G-CSF Receptor

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer