CD11b Rat Monoclonal Antibody [Clone ID: M1/70.15]

CAT#: SM014LE

CD11b rat monoclonal antibody, clone M1/70.15, Low Endotoxin


USD 745.00

5 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name M1/70.15
Applications FC, FN, IHC, IP
Recommended Dilution Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Paraffin Sections.
Immunoprecipitation.
Flow Cytometry: 1/50-1/100 (routinely tested on Mouse peritoneal macrophages).
Functional Assays: Clone M1/70.15 has been reported to block iC3b binding to its receptor.
Immunofluorescence.
Reactivities Human, Mouse, Rabbit
Host Rat
Isotype IgG2b
Clonality Monoclonal
Immunogen T cell enriched splenocytes from B10 mice.
Spleen cells from immunised DA rats were fused with cells of the NS1/1.Ag4.1 mouse myeloma cell line.
Specificity This antibody recognises the CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages.
Formulation State: Low Endotoxin
State: Liquid purified Ig fraction without preservatives.
Concentration 1.0 mg/ml
Purification Affinity Chromatography on Protein G.
Background The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages.
Synonyms ITGAM, CR3A, CR-3 alpha chain, Integrin alpha-M, MAC1
Note Endotoxin Level: < 0.01EU/µg
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.