Ifng Rat Monoclonal Antibody [Clone ID: XMG1.2]
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Specifications
Product Data | |
Clone Name | XMG1.2 |
Applications | ELISA, FC |
Recommended Dilution | ELISA: 1-10 µg/ml. Flow Cytometry: Use 10 µl of 1/10-1/50 diluted antibody to label 1x10e6 cells in 100 µl (Membrane permeablisation is required). |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG1 |
Clonality | Monoclonal |
Specificity | This antibody recognises IFN gamma. This reagent may be used for the detection of intracellular IFN gamma using flow cytometric techniques. |
Formulation | PBS containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction |
Concentration | 1.0 mg/ml |
Database Link | |
Background | Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2. |
Synonyms | IFN-gamma, gamma IFN |
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