HLAG (HLA-G) Mouse Monoclonal Antibody [Clone ID: MEM-G/1]

CAT#: SM1591

HLAG (HLA-G) mouse monoclonal antibody, clone MEM-G/1, Purified

Specifications

Product Data

• Clone Name: MEM-G/1
• Applications: IHC, WB
• Recommended Dilution: Western Blot: Reducing reagents are required.
  Immunohistochemistry on Paraffin Sections: 1/60-1/100.
  This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
  Recommended Positive Control: Human placenta- extravillous cytotrophoblast.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Denatured bacterially expressed recombinant Human HLA G heavy chain
• Specificity: This antibody reacts with denatured soluble and membrane bound HLA G heavy chain.
• Formulation: PBS containing 0.09% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography on Protein A
• Database Link:
  Entrez Gene 3135 Human
• Background: The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region.
  HLA G belongs to the HLA class I molecules (HLA Class Ib, nonclassical) and is involved in the presentation of foreign antigens to the immune system. This molecule is expressed on the surface of trophoblast cells and plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells.
• Synonyms: HLA-6.0, HLAG, MHC class I antigen G
• Note: Predicted Molecular Weight: 38 kDa.