Vimentin (VIM) Mouse Monoclonal Antibody [Clone ID: VI-RE/1]
Specifications
Product Data | |
Clone Name | VI-RE/1 |
Applications | FC |
Recommended Dilution | Flow cytometry. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Bacterially expressed full-length human vimentin |
Specificity | This antibody reacts with human vimentin, a 57 kDa intermediate filament protein expressed on a wide variety of mesenchymal and mesodermal cell types. |
Formulation | PBS, 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Label: APC State: Liquid Ig fraction Preservative: 15 mM sodium azide Label: The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
Concentration | lot specific |
Conjugation | APC |
Storage | Store undiluted at 2-8°C. DO NOT FREEZE! This products is photosensitive and should be protected from light. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | Vimentin (57 kDa) is the most ubiquituos intermediate filament protein and the first to be expressed during cell differentiation. All primitive cell types express vimentin but in most non-mesenchymal cells it is replaced by other intermediate filament proteins during differentiation. Vimentin is expressed in a wide variety of mesenchymal cell types - fibroblasts, endothelial cells etc., and in a number of other cell types derived from mesoderm, e.g., mesothelium and ovarian granulosa cells. In non-vascular smooth muscle cellsand striated muscle, vimentin is often replaced by desmin, however, during regeneration, vimentin is reexpressed. Cells of the lymfo-haemopoietic system (lymphocytes, macrophages etc.) also express vimentin, sometimes in scarce amounts. Vimentin is also found in mesoderm derived epithelia, e.g. kidney (Bowman capsule), endometrium and ovary (surface epithelium), in myoepithelial cells (breast, salivary and sweat glands), an in thyroid gland epithelium. In these cell types, as in mesothelial cells, vimentin is coexpressed with cytokeratin. |
Synonyms | VIM |
Reference Data |
Documents
Product Manuals |
FAQs |
{0} Product Review(s)
Be the first one to submit a review