ProDynorphin (PDYN) (1-13) Rabbit Polyclonal Antibody

CAT#: SP1216

ProDynorphin (PDYN) (1-13) rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: IHC, R
• Recommended Dilution: Radioimmunoassays: 1/5000.
  Immunohistochemistry on frozen sections: 1/250 - 1/2500.
• Reactivities: Guinea Pig, Hamster, Human, Monkey, Porcine, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, YGGFLRRQFKVVT, corresponding to full-length porcine dynorphin B (1-13), conjugated to thyroglobulin.
• Specificity: This antibody recognizes Dynorphin B (1-13), a secreted peptide which mimics the effects of opiate drugs.
• Formulation: PBS containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
  State: Serum
  State: Liquid serum
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
  Storage in frost free freezers is not recommended. Should this product contain a precipitate microcentrifugation before use is recommended.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens prodynorphin (PDYN), transcript variant 1
• Database Link:
  Entrez Gene 29190 RatEntrez Gene 5173 Human
• Background: Dynorphin is produced in many different parts of the brain, including the hypothalamus, the hippocampus and the spinal cord, and has many different physiological actions, depending upon its site of production. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. As such, it may help some individuals against addiction. Blocking dynorphin may help alleviate depression.
• Synonyms: PDYN, DynorphinB, Dynorphin-B, DynB, Dyn-B

Reference Data

• Protein Families: Secreted Protein